The shift towards open innovation has substantially changed the scientific and practical perception of corporate innovation. While scientific studies on open innovation are burgeoning, present research underlies a business-centric view that has focused on the back-end of the innovation process. The impact and implications of open innovation on academic and industrial science at the very front-end of the innovation process have so far been neglected. Our paper presents a conceptualization of open science and research as a peculiarity under the roof of open innovation. We propose four perspectives, outline current trends, and present directions for future developments.