Startups are a source of new ventures, products and services which are needed to compete in markets that may be highly disrupted by the internet, mobile computing, social media and other new technology platforms. This article develops an explicit account of the factors and contexts influencing internet- enabled startups and thereby conceives of entrepreneurship as an action- oriented phenomenon. The decomposition of the entrepreneurial process into discrete activity types gives insight into the range of behaviours, skills and resources required of entrepreneurs. Building on the data generated by the HIIG’s entrepreneurship research team — interviews with 94 startups in PhD- led Startup-Clinics between July 2013 and December 2014 — this article discusses the main supporting and hindering factors for internet-enabled startups in Berlin. The data enables policy makers to guide their decisions and to improve the overall startup community in Berlin and Germany.